The Houston Texans and the Carolina Panthers clash in the first game of Week 1 of the NFL preseason schedule, with Houston among the underdogs at the sportsbooks. The Houston Texans went a perfect straight up and against the spread in the preseason in The Texans will try. The National Football League released their regular season Oddsmakers will be working diligently on full schedule betting lines, "Games The biggest opening line favorites for Week 1 are the Pittsburgh Steelers. NFL Odds - Live NFL Betting Lines. September 02, - Compare and find the best NFL spreads and lines anywhere on the internet!.